The Editor in Chief oversees all Cochrane Library content, including Cochrane Reviews published in the Cochrane Database of Systematic Reviews. The Network Senior Editors report to the Editor in Chief and are responsible for the Cochrane Reviews (including protocols) published by Cochrane Review Groups (CRGs) in their Network.

Within each Network, the individual CRG's Co-ordinating Editor or nominated deputy must approve each Cochrane Review or protocol of a Cochrane Review before it can proceed for publication in the Cochrane Database of Systematic Reviews. Approval is also required by the Cochrane Diagnostic Test Accuracy Editorial Team for Diagnostic Test Accuracy Cochrane Reviews or protocols for Cochrane Reviews.

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