Arm vs Contrast level data

RevMan can manage two types of results data in the analyses: 

  1. Arm level data: When data for all study intervention arms are available, such as the number of cases or events for each arm or mean effect sizes for each arm.
  2. Contrast level data: If only effect estimates for comparing the intervention arms are available, e.g. mean difference, (adjusted) odds ratio, hazard ratios. It is possible to use either of these sets of data, or combine them together.

With automatic analyses (under ‘Data source’), you can choose to include:

    1. Only arm-level data
    2. Only contrast-level data
    3. Contrast- and arm-level data (preferring arm-level data where both exist)
    4. Contrast- and arm-level data (preferring contrast-level data where both exist) 

Section 5.3.6 of the Cochrane Handbook for Systematic Reviews of Interventions provides more guidance on the different types of data and in what circumstances either might be preferred in your analyses. 

Here is an example of arm level data: 

Study ID

Intervention

Arm

Events

Total

Herne 1980XibornolicsXibornolics322
TetracyclineTetracycline424
PlaceboPlacebo1022

McKerrow 1961

Tetracycline

Tetracycline

5

15

Placebo

Placebo

8

18

Taylor 1977

Co-trimoxazol

Co-trimoxazol

12

29

Placebo

Placebo

3

59

Here is an example of contrast level data:

Study ID

Intervention

Arm

Reference arm

Log[Odds ratio]

Standard error

Covariance
Hoaglund 1950AeromycinAeromycinNo-1.20.30.03
TetracyclineTetracyclineNo-1.40.5-
PlaceboPlaceboYes---

Kaiser 1996

Co-amoxiclav

Co-amoxiclav

No

-0.7

0.9

-

Placebo

Placebo

Yes

-

-

-

Lexomboon 1971

Penicillin V

Penicillin V

No

-0.9

0.2

-
PlaceboPlaceboYes---