Airways
COPD exacerbation management
The COS-AECOPD @EuroRespSoc Task Force is developing a core outcome set (COS) for #COPD exacerbation management.
coreASTHMA project
5 outcomes for use in phase 3 and phase 4 clinical drug trials in moderate-to-severe asthma |
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severe asthma exacerbation |
change in asthma control |
asthma-specific or severe asthma-specific quality of life |
asthma-specific hospital stay (i.e. >24 hour stays at any level of care) or admission |
asthma-specific emergency department visit |
Kidney & Transplant
Cochrane Kidney & Transplant is using core outcomes developed by the SONG initiative based at the Centre for Kidney Research.
Since 2017 Cochrane Kidney & Transplant has adopted the standardised core outcomes for HD & Tx into their protocols and reviews.
SONG initiative
Outcome sets | Outcomes |
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Haemodialysis (SONG-HD) |
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Transplantation (SONG-Tx) |
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Peritoneal dialysis (SONG-PD) |
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Children and adolescents (SONG-Kids) |
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SONG Handbook
See page 16 for the core outcomes and other tiered outcomes.
SONG_Handbook_v01_20170601-published.pdf
Skin
Cochrane Skin partners with Cochrane COUSIN, who are co-ordinating the work of developing a whole variety of core outcome sets on dermatology disease areas.
One area that is very well developed COS eczema, developed at the Centre of Evidence Based Dermatology where Cochrane Skin are based.
4 core outcome domains
Outcome domains | Validated instruments |
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| EASI |
| POEM |
| In progress |
| In progress |
http://www.homeforeczema.org/research/index.aspx