Cochrane

# Supplementary material 18 to:
Interventions for preventing falls in older people living in the community

Gillespie LD , Robertson MC , Gillespie WJ , Sherrington C , Gates S , Clemson L , Lamb SE
https://doi.org/10.1002/14651858.CD007146.pub3

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# Sensitivity analyses exploring impact of risk of bias on effect sizes

Intervention | Number of trials (participants) in the analysis | Pooled effect size, 95% CI | Number of trials (participants) in the sensitivity analysisa | Pooled effect size, 95% CI | Impact
--- | --- | --- | --- | --- | ---
Group exercise: multiple categories of exercise (Analysis 1.1.1) | 16 (3622) | RaR 0.71, 95% CI 0.63 to 0.82 | 11 (2978) | RaR 0.79, 95% CI 0.71 to 0.88 | Remained statistically significant
Group exercise: multiple categories of exercise (Analysis 1.2.1) | 22 (5333) | RR 0.85, 95% CI 0.76 to 0.96 | 12 (2454) | RR 0.86, 95% CI 0.79 to 0.94 | Remained statistically significant
Individual exercise at home: multiple categories of exercise (Analysis 1.1.2) | 7 (951) | RaR 0.68, 95% CI 0.58 to 0.80 | 4 (559) | RaR 0.69, 95% CI 0.55 to 0.86 | Remained statistically significant
Individual exercise at home: multiple categories of exercise (Analysis 1.2.2) | 6 (714) | RR 0.78, 95% CI 0.64 to 0.94 | 3 (386) | RR 0.81, 95% CI 0.63 to 1.04 | No longer statistically significant
Group exercise: Tai Chi (Analysis 1.1.4) | 5 (1563) | RaR 0.72, 95% CI 0.52 to 1.00 | 4 (1375) | RaR 0.81, 95% CI 0.61 to 1.09 | No longer statistically significant
Group exercise: Tai Chi (Analysis 1.2.4) | 6 (1625) | RR 0.71, 95% CI 0.57 to 0.87 | 3 (1239) | RR 0.80, 95% CI 0.67 to 0.95 | Remained statistically significant
Group exercise: gait, balance or functional training (Analysis 1.1.5) | 4 (519) | RaR 0.72, 95% CI 0.55 to 0.94 | 1 (303) | RaR 0.82, 95% CI 0.58 to 1.17 | No longer statistically significant
Cardiac pacing (Analysis 12.1.1) | 3 (349) | RaR 0.73, 95% CI 0.57 to 0.93 | 3 (349) | RaR 0.73, 95% CI 0.57, 0.93 | Unchanged
Home safety intervention (OT) (Analysis 17.1.1) | 4 (1446) | RaR 0.69, 95% CI 0.55 to 0.86 | 4 (1446) | RaR 0.69, 95% CI 0.55 to 0.86 | Unchanged
Home safety intervention (OT) (Analysis 17.2.1) | 5 (1156) | RR 0.79, 95% CI 0.69 to 0.90 | 4 (1146) | RR 0.79, 95% CI 0.69 to 0.90 | Unchanged
Multifactorial intervention (Analysis 22.1) | 19 (9503) | RaR 0.76, 95% CI 0.67 to 0.86 | 16 (8153) | RaR 0.80, 95% CI 0.72 to 0.87 | Remained statistically significant

aAfter removing trials assessed as high risk of bias in one or more key domains: random sequence generation (selection bias), allocation concealment (selection bias), blinding of outcome assessors (detection bias), and incomplete outcome data (attrition bias).