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Cochrane has robust, open, and methodologically mature processes aimed at ensuring that Cochrane Reviews provide the best available evidence of the effects of healthcare interventions. These include documented methodologies, training, peer review, an open feedback system, and a willingness to embrace continuous improvement. However, it can be expected that, despite these best endeavours, flaws may appear in Cochrane Reviews from time to time.

A serious error occurs when:

The Editor in Chief must be notified of all suspected or confirmed serious errors. The Editor in Chief along with the Co-ordinating Editor of the Cochrane Review Group (CRG) that published the Cochrane Review will investigate and agree a course of action.

Also see the policy for withdrawing published Cochrane Reviews.