Basic steps

Each step is hyperlinked to a brief demo video.

1. Search the COVID-19 Register for studies
2. Login to CRS Web & select COVID-19 Register (make sure you have ticked IN REGISTER as you do not want to search beyond this)
3. Within the CRS Web search for study using the title or study ID
4. Open annotation widget within the record to annotate

Annotation

detail 

Terms not already in vocabulary

• our Vocabulary browser is available HERE

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Priority studies to annotate

For both priority 1 and 2 please search for

The reference type can be selected on our Study Register

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Priority 1

Limit search to

• Study Reference Type: Journal Article/Preprint Article
• Intervention Assignment: Randomised 

Any of the following interventions:

1. Hand cleaning with ash
2. Convalescent plasma, convalescent serum or convalescent hyperimmune immunoglobulin 
3. Any intervention in which a core component involves the use of the internet to facilitate video calls or video conferencing through computers, smartphones or tablets
4. chloroquine, remdesivir, or corticosteroids

Priority 2

• Study Reference Type: Journal Article/Preprint Article
• Intervention Assignment: Non-randomised or Unclear or Quasi-randomised 

Any of the following interventions:

1. Hand cleaning with ash
2. Convalescent plasma, convalescent serum or convalescent hyperimmune immunoglobulin 
3. Any intervention in which a core component involves the use of the internet to facilitate video calls or video conferencing through computers, smartphones or tablets
4. chloroquine, remdesivir, or corticosteroids

Searching to identify priority trials

• Search on https://covid-19.cochrane.org/ 

1. Restrict to Study Type: Interventional
2. For the specific interventions:
   1. Text search for ash* 
   2. Text search for convalescent
   3. etc.

Duplicate study records

You may come across some duplicate records where the same study has been imported from different sources (e.g. trials registers, pubmed). 

If you find any:

• insert the study ID adn state 'duplicate' in the MISC 1 field
• annotate ONLY one record, preferably the published report (jnl article or preprint)

Topics/vocabulary

• Before you start annotating please check that the Cochrane Linked Data Vocabulary to determine whether or not terms are available
• If not available, place your request in the covid19-study-annotation channel in Slack and alert Anna last

Vocabulary notes

Age

A number of studies will state in their inclusion criteria Aged 18 years or older. Please annotate as:

Drug combinations

Use the individual drugs with AND

At Risk Of

In some studies the inclusion criteria population is 'At risk of ...' - in this case we do not annotate the condition in the Population but only as an Outcome.

Table of misc. terms and their categories

Time to ...

Outcome annotation examples