...
...
| maxLevel | 3 |
|---|
Workflow
Initial workflow
...
...
...
BAU workflow
(yet to be determined/in discussion)
Prioritisation of study type
- Interventional - the annotators mentioned above will annotate these studies
- RCT
- Other
- Diagnostic/Prognostic - being annotated by others
- Observational & other types
Guidance for annotation
(more detailed step by step guidance) Deirdre to insert
Annotation widget
We have imported the annotation widget, that we use for systematic review annotation, in to the CRS Web.
...
- The register will be listed with any other registers that you access via the CRS Web
- Search and layout is identical to that in other CRS registers
- Additional fields have been added to the CRS records to assist us in our workflow
...
| title | Click here to view additional fields |
|---|
- Register for studies
- Login to CRS Web & select COVID-19 Register (make sure you have ticked IN REGISTER as you do not want to search beyond this)
- Within the CRS Web search for study using the title or study ID
- Open annotation widget within the record to annotate
Annotation detail
Required | Not required | Notes |
|---|
...
when an annotation is completed this field will be autofilled with the users name
...
there are two options here, In Progress or Vocabulary Request.
...
- Three annotation status are available
...
| title | Click here for list ot status |
|---|
...
Status
...
Description
...
Available for annotation
...
record is available for anyone to annotate
...
Annotating
...
the record is open and being annotated by another person
...
Annotated
...
annotation has been completed
Annotation detail required
...
PICO component
...
| Population/Condition |
| |||
| Intervention |
|
...
| If the study is comparing dosage please insert this data | |||
| Comparator |
| |||
| Outcomes |
|
...
|
| For each outcome create a new group |
Terms not already in vocabulary
- our Vocabulary browser is available HERE
| Info | ||
|---|---|---|
| ||
In some cases you will not be able to complete a full annotation. We ask that you:
|
...
|
| HTML |
|---|
<a href="#com-atlassian-confluence">Back to Top</a> |
Priority studies to annotate
These may change over time depending on topics to be coved in rapid reviews.
Highest Priority
Intervention Assignment: Randomised and:
Any of the following interventions:
- Hand cleaning with ash
- Convalescent plasma, convalescent serum or convalescent hyperimmune immunoglobulin
- Any intervention in which a core component involves the use of the internet to facilitate video calls or video conferencing through computers, smartphones or tablets
- chloroquine, remdesivir, or corticosteroids
Priority 2
Intervention Assignment: Non-randomised or Unclear or Quasi-randomised and:
Any of the following interventions:
- Hand cleaning with ash
- Convalescent plasma, convalescent serum or convalescent hyperimmune immunoglobulin
- Any intervention in which a core component involves the use of the internet to facilitate video calls or video conferencing through computers, smartphones or tablets
- chloroquine, remdesivir, or corticosteroids
Searching the backlog on https://covid-19.cochrane.org/ to identify priority trials
Restrict to Study Type: Interventional
For the specific interventions:
...
Duplicate study records
You may come across some duplicate records where the same study has been imported from different sources (e.g. trials registers, pubmed).
If you find any:
- insert the study ID adn state 'duplicate' in the MISC 1 field
- annotate ONLY one record, preferably the published report (jnl article or preprint)
...
Topics/vocabulary
- Before you start annotating please check that the Cochrane Linked Data Vocabulary to determine whether or not terms are available
- If not available, place your request in the covid19-study-annotation channel in Slack and alert Anna last
Vocabulary notes
Age
A number of studies will state in their inclusion criteria Aged 18 years or older. Please annotate as:
| Young Adult 19-24 years or Adult 19-44 years or Middle Aged 45-64 years or Aged 65-79 years or Aged 80 and over 80+ years |
Drug combinations
Use the individual drugs with AND
At Risk Of
In some studies the inclusion criteria population is 'At risk of ...' - in this case we do not annotate the condition in the Population but only as an Outcome.
Table of misc. terms and their categories
| Table Filter | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||||||||||||||||||||||
|
...
|
Time to ...
| Time to Clinical Improvement | https://data.cochrane.org/concepts/1ZAQeEkwo0cpmW |
| Time to Clinical Recovery | https://data.cochrane.org/concepts/OW7PMP5pAaCBgR |
| Time to defervescence | https://data.cochrane.org/concepts/6nyXkn9P8DIPG3 |
| Time to cough | Cough |
| Time to Dyspnea | Dyspnea |
Time till the virus nucleic acid test goes negative/ Transition time of novel coronavirus nucleic acid" |
Outcome annotation examples
| Study | Outcome | Outcome detail | Annotation |
|---|---|---|---|
| NCT04278963 | respiratory progression | Defined as: SPO2≤ 93% on room air or PaO2/FiO2≤ 300mmHg and requirement for supplemental oxygen or more advanced ventilator support | Hypoxia AND (Oxygen therapy OR mechanical ventilation) - all in the same outcome group |
...