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Where synonyms or near-synonyms appear in the controlled vocabularies that we will use the following processes to standardize annotations (as much as possible). |
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There is now a type-ahead function in the PICO annotator that shows the frequency of term use (i.e. the number of times a term has been used by annotators is displayed immediately after each term in the drop-down menu for each PICO component). |
A term in one vocabulary has a synonymous term in the same vocabulary
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For some reason, MedDRA has been structured so that every term at the second-lowest level of its hierarchy (PT - Preferred Term) has a synonymous term at it's lowest level (LLT - Lowest Level Term). The LLT member of each of these pairs has been removed from our Cochrane Vocabulary, so there should be no exactly identical terms within MedDRA. Update: most of these synonymous terms have been removed, but if you uncover any examples in the course of annotation or QA, please flag them up for us to resolve. However, there will be many close matches within MedDRA - for example UK and US spellings of a term (oedema, edema etc.) are separate terms in MedDRA. We are in the process of resolving this This will be resolved in a way that will merge these MedDRA synonyms.
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- If one of the MedDRA synonyms is linked to a SNOMED term, pick that one.
- If a UK spelling exists, please use it.
- If neither of the above exists, just pick any one of a group of MedDRA terms that seem to be synonyms and we will be able to merge your annotation with annotations using one of the other terms.
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