General information
Tools for COVID-19 annotation
Annotation widget
- We have imported the annotation widget, that we use for systematic review annotation, in to the CRS Web
- If you cannot access the CRS Web please contact Deirdre Beecher
- The register will be listed with any other registers that you access via the CRS Web
- Search and layout is identical to that in other CRS registers
Annotation status & fields
- Additional fields have been added to the CRS records to assist us in our workflow
title | Click here to view additional fields |
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when an annotation is completed this field will be autofilled with the users name
there are two options here, In Progress or Vocabulary Request.
- Three annotation status are available
title | Click here for list ot status |
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Status
Description
Available for annotation
record is available for anyone to annotate
Annotating
the record is open and being annotated by another person
Annotated
annotation has been completed
Basic steps
Each step is hyperlinked to a brief demo video.
- Search the COVID-19 Register for studies
- Login to CRS Web & select COVID-19 Register (make sure you have ticked IN REGISTER as you do not want to search beyond this)
- Within the CRS Web search for study using the title or study ID
- Open annotation widget within the record to annotate
Annotation detail required
Population/Condition | Intervention | Comparator | Outcomes |
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- dosage, schedule etc not required unless is the comparison
Terms not already in vocabulary
- our Vocabulary browser is available HERE
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In some cases you will not be able to complete a full annotation. We ask that you:
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HTML |
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<a href="#com-atlassian-confluence">Back to Top</a> |
Priority studies to annotate
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These may change over time depending on topics to be coved in rapid reviews. |
For both priority 1 and 2 please search for
- studies with results (journal article or preprint article) then
- trial registry records
The reference type can be selected on our Study Register
Priority 1
Limit search to
- Study Reference Type: Journal Article/Preprint Article
- Intervention Assignment: Randomised
Any of the following interventions:
- Hand cleaning with ash
- Convalescent plasma, convalescent serum or convalescent hyperimmune immunoglobulin
- Any intervention in which a core component involves the use of the internet to facilitate video calls or video conferencing through computers, smartphones or tablets
- chloroquine, remdesivir, or corticosteroids
Priority 2
- Study Reference Type: Journal Article/Preprint Article
- Intervention Assignment: Non-randomised or Unclear or Quasi-randomised
Any of the following interventions:
- Hand cleaning with ash
- Convalescent plasma, convalescent serum or convalescent hyperimmune immunoglobulin
- Any intervention in which a core component involves the use of the internet to facilitate video calls or video conferencing through computers, smartphones or tablets
- chloroquine, remdesivir, or corticosteroids
Searching to identify priority trials
- Search on https://covid-19.cochrane.org/
- Restrict to Study Type: Interventional
- For the specific interventions:
- Text search for ash*
- Text search for convalescent
- etc.
Duplicate study records
You may come across some duplicate records where the same study has been imported from different sources (e.g. trials registers, pubmed).
If you find any:
- insert the study ID adn state 'duplicate' in the MISC 1 field
- annotate ONLY one record, preferably the published report (jnl article or preprint)
Topics/vocabulary
- Before you start annotating please check that the Cochrane Linked Data Vocabulary to determine whether or not terms are available
- If not available, place your request in the covid19-study-annotation channel in Slack and alert Anna last
Vocabulary notes
Age
A number of studies will state in their inclusion criteria Aged 18 years or older. Please annotate as:
Young Adult 19-24 years or Adult 19-44 years or Middle Aged 45-64 years or Aged 65-79 years or Aged 80 and over 80+ years |
Drug combinations
Use the individual drugs with AND
At Risk Of
In some studies the inclusion criteria population is 'At risk of ...' - in this case we do not annotate the condition in the Population but only as an Outcome
Table of misc. terms and their categories
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Time to ...
Time to Clinical Improvement | https://data.cochrane.org/concepts/1ZAQeEkwo0cpmW |
Time to Clinical Recovery | https://data.cochrane.org/concepts/OW7PMP5pAaCBgR |
Time to defervescence | https://data.cochrane.org/concepts/6nyXkn9P8DIPG3 |
Time to cough | Cough |
Time to Dyspnea | Dyspnea |
Time till the virus nucleic acid test goes negative/ Transition time of novel coronavirus nucleic acid" |
Outcome annotation examples
Study | Outcome | Outcome detail | Annotation |
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NCT04278963 | respiratory progression | Defined as: SPO2≤ 93% on room air or PaO2/FiO2≤ 300mmHg and requirement for supplemental oxygen or more advanced ventilator support | Hypoxia AND (Oxygen therapy OR mechanical ventilation) - all in the same outcome group |